Mechanisms of Synapse Assembly and Disassembly
نویسندگان
چکیده
منابع مشابه
Mechanisms of Synapse Assembly and Disassembly
The mechanisms that govern synapse formation and elimination are fundamental to our understanding of neural development and plasticity. The wiring of neural circuitry requires that vast numbers of synapses be formed in a relatively short time. The subsequent refinement of neural circuitry involves the formation of additional synapses coincident with the disassembly of previously functional syna...
متن کاملReview Mechanisms of Synapse Assembly and Disassembly Entiation Is Necessary for Subsequent Induction of Pre
it has been observed to occur in the absence of the presynaptic motoneurons, demonstrating that it is independent of a motoneuron-derived signal (Yang et al., Yukiko Goda1,* and Graeme W. Davis2,* MRC Cell Biology Unit and Laboratory for Molecular Cell Biology 2000, 2001; Lin et al., 2001; Arber et al., 2002). At present University College London it is unclear how muscle prepattern is establish...
متن کاملUbiquitin code assembly and disassembly
Ubiquitin, a 76 amino-acid polypeptide, presents a compact three-dimensional structure, utilising a fold that recurs within larger polypeptides and in other protein modifiers, such as NEDD8 and SUMO. Ubiquitylation was initially recognised as a signal for proteasome-mediated degradation. We shall consider here how this view has evolved to appreciate that the dynamic appendage of different types...
متن کاملMechanisms of actin disassembly
The actin cytoskeleton is constantly assembling and disassembling. Cells harness the energy of these turnover dynamics to drive cell motility and organize cytoplasm. Although much is known about how cells control actin polymerization, we do not understand how actin filaments depolymerize inside cells. I briefly describe how the combination of imaging actin filament dynamics in cells and using i...
متن کاملAssembly and disassembly of DNA polymerase holoenzyme.
The complex task of genomic replication requires a large collection of proteins properly assembled within the close confines of the replication fork. The mechanism and dynamics of holoenzyme assembly and disassembly have been investigated using steady state and pre-steady state methods as opposed to structural studies, primarily due to the intrinsic transient nature of these protein complexes d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuron
سال: 2003
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(03)00608-1